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BioRender Template
cGAS Detects Cytosolic DNA
Description
This template shows how cGAS detects cytosolic DNA, converting ATP and GTP into 2'3'-cGAMP, which activates STING, TBK1, and IRF3 at the endoplasmic reticulum, leading dimerized phosphorylated IRF3 to enter the nucleus and induce type I interferon gene expression.
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