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BioRender Template
Chaperone-Mediated Autophagy (CMA)
Description
This template shows chaperone-mediated autophagy in four steps: recognition of a KFERQ motif on a substrate protein by the Hsc70 chaperone complex, binding to the LAMP-2A receptor, translocation into the lysosome assisted by GFAP, and dissociation of the complex mediated by phosphorylated GFAP, followed by protein degradation.
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