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BioRender Template
Cholinergic Anti-Inflammatory Pathway
Description
This template illustrates the cholinergic anti-inflammatory pathway, showing how the efferent vagus nerve releases acetylcholine that binds a7nAChR on macrophages to suppress cytokine production in response to pathogens, ischemia, injury, or cytokines. Reduced cytokine release, including TNF, IL-1, and HMGB1, is detected by the afferent vagus nerve back to the nucleus tractus solitarius, supporting tissue recovery.
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