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BioRender Template
Chronic Active & Tonic BCR Signaling Pathways
Description
This template compares chronic active and tonic B cell receptor signaling pathways, showing how antigen binding to the BCR and CD79A/CD79B chains activates SFK and SYK kinases that branch into MAPK, PI3K, NFAT, and NF-kB pathways in chronic active signaling. Tonic signaling in the absence of strong antigen engagement is shown activating only the PI3K pathway through AKT and mTOR.
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