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CM-272, a First-in-class, Reversible and Dual G9a/DNMTs Inhibitor

An editable high resolution scientific image depicting CM-272, a First-in-class, Reversible and Dual G9a/DNMTs Inhibitor

Description

Schematic representation of some components of the repressor complex that regulates transcription. CM-272 inhibits G9a and DNMT1 activities, disrupting the interaction of the different components. Combination strategies using CM-272 with other drugs result in synergistic cancer cell death.
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