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BioRender Template
Conventional vs. Self-Amplifying mRNA Vaccines
Description
This template compares conventional and self-amplifying mRNA vaccine mechanisms side by side, tracing mRNA carriers through the endosome to produce protein that is degraded by the proteasome and presented as peptides on MHC complexes. The self-amplifying mRNA side includes alphavirus nonstructural proteins that allow the mRNA to replicate itself, producing more protein and a greater number of MHC complexes displaying peptides.
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