CREB Signaling Pathway
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Description:
This template shows the CREB signaling pathway, tracing three membrane receptor inputs, a G-protein coupled receptor, an ion channel, and a receptor tyrosine kinase, into converging intracellular signals. These signals pass through protein kinase A, calcium/calmodulin kinase IV, and MAPK to phosphorylate CREB, which then binds the CRE DNA element to activate transcription.
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This template shows the CREB signaling pathway, tracing three membrane receptor inputs, a G-protein coupled receptor, an ion channel, and a receptor tyrosine kinase, into converging intracellular signals. These signals pass through protein kinase A, calcium/calmodulin kinase IV, and MAPK to phosphorylate CREB, which then binds the CRE DNA element to activate transcription.