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BioRender Template
Cytokine Release Syndrome
Description
This template shows the progression of cytokine release syndrome, starting with activation or lysis of T cells and B cells releasing IFN-gamma and TNF-alpha, which activate macrophages, endothelial cells, and dendritic cells in a feedback loop. A side chart ranks severity from Grade 1, with fever and constitutional symptoms, to Grade 4, requiring mechanical ventilation and high grade organ toxicities.
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