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dCas9-KRAB Transcriptional Repression System

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Description: This base template provides a general overview of a CRISPR/dCas9 transcriptional repression system. dCas9 protein is in complex with a KRAB protein (a transcription repressor), binding to a specific DNA sequence guided by sgRNA. This CRISPR-mediated system allows regulation of gene expression. This template can be used as a starting point for more complex workflows that use CRISPR/dCas9 systems as transcriptional repressors.

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BioRender Template FAQs

What does the dCas9-KRAB Transcriptional Repression System template show?

This base template provides a general overview of a CRISPR/dCas9 transcriptional repression system. dCas9 protein is in complex with a KRAB protein (a transcription repressor), binding to a specific DNA sequence guided by sgRNA. This CRISPR-mediated system allows regulation of gene expression. This template can be used as a starting point for more complex workflows that use CRISPR/dCas9 systems as transcriptional repressors.

Is the dCas9-KRAB Transcriptional Repression System template free to use?

Yes, you can customize this template with a free BioRender account (no credit card required). Paid plans unlock additional export formats, higher-resolution downloads, and publication permissions.

Can I edit or customize this template?

Yes, every element is fully editable. Icons, labels, colors, arrows, shapes and layout can all be changed to match your preferences or needs using BioRender's drag-and-drop editor. You can add or remove elements to fully customize your use case.

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Unlock publication permissions with a paid plan, and include 'Created with BioRender.com' in your figure legend, or cite BioRender directly per your journal's guidelines.

What is dCas9-KRAB Transcriptional Repression System used for / who typically uses this template?

Researchers and scientists use this template for publications, funding proposals, grant applications, presentations, posters, and more.