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Dengue virus inhibition by sulfated polysaccharides

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Alexandre Orsato

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Description: Dengue virus enters into mammalian cells by first interacting with a host cell receptor, heparan sulfate, leading to dengue infection. By mimicking heparan sulfate, sulfated polysaccharides can interact with dengue virus and block the entering step, leading to the inhibition of dengue infection.

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What does the Dengue virus inhibition by sulfated polysaccharides template show?

Dengue virus enters into mammalian cells by first interacting with a host cell receptor, heparan sulfate, leading to dengue infection. By mimicking heparan sulfate, sulfated polysaccharides can interact with dengue virus and block the entering step, leading to the inhibition of dengue infection.

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