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Detecting neurochemical release using fiber photometry

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Aria Walls

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Description: Fiber photometry (FP) utilizes G-protein-coupled receptor (GPCR) activation-based (GRAB) sensors to measure relative concentrations of extracellular ligands. In combination with a fiber optic ferrule, the population-level release activity of neurons can be approximated by the fluorescent output of locally expressed GRAB sensors.

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Fiber photometry (FP) utilizes G-protein-coupled receptor (GPCR) activation-based (GRAB) sensors to measure relative concentrations of extracellular ligands. In combination with a fiber optic ferrule, the population-level release activity of neurons can be approximated by the fluorescent output of locally expressed GRAB sensors.

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