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Differentiation of TH1 Cells - Indirect and direct activation of T cells by TLR agonists

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Catherine C

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BioRender Team

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Description: This template shows dendritic cell maturation triggered by PAMPs binding TLRs, after which the mature dendritic cell presents antigen to a naive T cell via MHC II, TCR, and CD80/CD86-CD28 interactions while secreting TGF-beta and IL-6. These cytokines, along with IL-1, IL-23, and IL-18 acting on a gamma delta T cell, drive differentiation into a TH17 cell that produces IL-17 in a feedback loop.

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What does the Differentiation of TH1 Cells - Indirect and direct activation of T cells by TLR agonists template show?

This template shows dendritic cell maturation triggered by PAMPs binding TLRs, after which the mature dendritic cell presents antigen to a naive T cell via MHC II, TCR, and CD80/CD86-CD28 interactions while secreting TGF-beta and IL-6. These cytokines, along with IL-1, IL-23, and IL-18 acting on a gamma delta T cell, drive differentiation into a TH17 cell that produces IL-17 in a feedback loop.

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