BioRender Template

Direct Pathways of Nose-to-Brain Biomolecule Delivery

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Mina Nashed

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BioRender Team

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Description: This template compares two direct pathways of nose-to-brain biomolecule delivery after intranasal administration, the respiratory pathway along the trigeminal nerve through the cribriform plate toward the brainstem, and the olfactory pathway through transcellular, paracellular, and intracellular routes across the olfactory epithelium into the olfactory bulb. Cross-section insets show biomolecules crossing the mucus layer and epithelium to reach the cerebrospinal fluid in each pathway.

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What does the Direct Pathways of Nose-to-Brain Biomolecule Delivery template show?

This template compares two direct pathways of nose-to-brain biomolecule delivery after intranasal administration, the respiratory pathway along the trigeminal nerve through the cribriform plate toward the brainstem, and the olfactory pathway through transcellular, paracellular, and intracellular routes across the olfactory epithelium into the olfactory bulb. Cross-section insets show biomolecules crossing the mucus layer and epithelium to reach the cerebrospinal fluid in each pathway.

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