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BioRender Template
DLL3 Targeting in Small Cell Lung Cancer
Description
This template compares Notch-1 signaling in a normal lung cell versus a small cell lung cancer cell, showing how DLL3 is retained intracellularly in vesicles in normal cells but accumulates on the cell surface in cancer cells. The cancer side shows increased DLL3 surface expression and increased Notch degradation compared to the normal cell, which shows balanced trafficking and Notch-1 activation.
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