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BioRender Template
DNA Methylation Levels During Mammalian Development
Creator
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Description
This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication.
During prenatal development, highly methylated primordial germ cells (PGCs) undergo methylation before gametes are re-methylated in a sex-specific manner. Following fertilization, methylation of the inherited oocyte and sperm genomes are differentially erased during preimplantation embryo development. Imprinted genes and intracisternal A-type particles, however, remain highly methylated. New methylation is established associated with cell differentiation.
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