Engineered Recellularized Bone Grafts for TMJ Regeneration

This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication. This template describes the process of engineering autologous graft in a preclinical porcine model. In particular, it can be used for repairing the ramus-condyle unit of the temporomandibular joint (TMJ). An anatomically precise scaffold is created using image-guided milling technique on a bovine decellularized mandible. The scaffold is then seeded with porcine adipose-derived stromal cells and cultured in a perfusion bioreactor. Finally, the obtained recellularized scaffold is orthotopically implanted in the porcine model. The graft can be explanted for further functional, structural, and molecular analyses.

Yes, you can customize this template with a free BioRender account (no credit card required). Paid plans unlock additional export formats, higher-resolution downloads, and publication permissions.

Yes, every element is fully editable. Icons, labels, colors, arrows, shapes and layout can all be changed to match your preferences or needs using BioRender's drag-and-drop editor. You can add or remove elements to fully customize your use case.

Yes, BioRender icons and templates meet journal, grant, and copyright standards for publication, and many researchers cite BioRender directly in their figure legends.

Unlock publication permissions with a paid plan, and include 'Created with BioRender.com' in your figure legend, or cite BioRender directly per your journal's guidelines.

Researchers and scientists use this template for publications, funding proposals, grant applications, presentations, posters, and more.