Epigenetic effect of butyrate

Butyrate is a histone deacetylase (HDAC) inhibitor. Inhibition of HDAC activity leads to incresed acetylation of histones and causes histone hyperacetylation. Histone tail acetylation increases the accessibility of a gene to the transcriptional machinery by causing the DNA to loosely associate with the histone proteins. Histone deacetylation causes histone tails to become highly charged and cause DNA to tightly bind to histones, so it becomes less accessible for transcription.

Yes, you can customize this template with a free BioRender account (no credit card required). Paid plans unlock additional export formats, higher-resolution downloads, and publication permissions.

Yes, every element is fully editable. Icons, labels, colors, arrows, shapes and layout can all be changed to match your preferences or needs using BioRender's drag-and-drop editor. You can add or remove elements to fully customize your use case.

Yes, BioRender icons and templates meet journal, grant, and copyright standards for publication, and many researchers cite BioRender directly in their figure legends.

Unlock publication permissions with a paid plan, and include 'Created with BioRender.com' in your figure legend, or cite BioRender directly per your journal's guidelines.

Researchers and scientists use this template for publications, funding proposals, grant applications, presentations, posters, and more.