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Epithelial-Mesenchymal Transition Occurrence
Description
EMT is essential for embryogenesis, tissue regeneration, and tumorigenesis. Its induction is regulated by kinase signaling, posttranslational modifications, and epigenetic mechanisms. EMT grants cells high plasticity, allowing transitions across the mesenchymal–epithelial spectrum to adapt to varying conditions, driving development, regeneration, and cancer progression. Adapted from Spatial and Temporal Relationship between Epithelial–Mesenchymal Transition (EMT) and Stem Cells in Cancer.
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