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Examples of the intersection of microbial mechanisms with cancer hallmarks
Description
The cancer hallmarks are described by Hanahan & Weinberg (2000, 2011). Microbiota-derived metabolites, genotoxins, and antigens influence host antitumor immunity, inflammation, energetics, cellular signaling, and metastasis. dsDNA, double-stranded DNA; mAb, monoclonal antibody; MDSC, myeloid-derived suppressor cell; MMP, matrix metalloproteinase; NKT cell, natural killer T cell; SCFAs, short-chain fatty acids.
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