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BioRender Template
Exosome-related metabolic priming of metastatic niche
Creator
s
Description
Metabolic reprogramming allows primary tumor cells to invade surrounding tissue, particularly through increased production of lactate from boosted glycolysis resulting in acidification of tumor microenvironment (TME). Primary tumors have also the innate capacity to educate the pre-metastatic niche (PMN) by shedding exosomes.
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