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BioRender Template
Expression of hM4Di in the Forebrain Excitatory Neuron Improves Stroke Outcome
Description
This template shows how expressing the inhibitory DREADD receptor hM4Di in forebrain excitatory neurons of the motor cortex, activated by the ligand CNO, opens GIRK potassium channels through G-protein subunits. This intervention decreases infarct volume in the mouse brain after stroke, indicating improved stroke outcome.
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