BioRender Template

Extracellular Matrix (ECM) Sequestering Peptides

Created by

Ariella Shikanov

•

BioRender Team

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Description:

Synthetic matrices offer a high degree of control and flexibility in mimicking the extracellular matrix (ECM) functions of native tissue. However, they are inert and inefficient at retaining cell-secreted extracellular molecules. Through functionalization of degradable poly(ethylene glycol) hydrogels with ECM-sequestering peptides, the synthetic matrices can be made more effective at recreating cell-matrix interactions, and thus more capable of recapitulating the native ECM composition.

Updated

August 2026

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