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BioRender Template
Flavonoids modulate autophagy pathways in cancer.
Creator
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Description
Beclin1 phosphorylation and the activation of the PI3KC3 complex convert PIP2 to PIP3, which recruits Wipi proteins and some autophagy-related genes in order to generate a single-layer pre-autophagosome (in blue). p62 interacts with the autophagy target and binds to active LC3-II, forming a mature double membrane (in purple) that is fused with lysosomes.
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