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Flavonoids modulate growth pathways in cancer.
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Description
Flavonoids inhibit the AKT/mTOR and Ras/ERK signaling pathway, impairing especially the metabolism, proliferation, survival, growth, and angiogenesis in cancer cells. Flavonoids inhibit AKT, preventing the activation of mTOR. The compounds directly inhibit mTOR. Epi: Epigallocatechin, Kae: Kaempferol; Myr: Myricetin; Que: Quercetin; Api: Apigenin; Gen: Genistein; Dai: Daidzein; Lut: Luteolin; Nar: Naringenin; Tax: Taxifolin; Eri: Eriodictyol; Vit: Vitexin.
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