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From Oral Intake to Circulation: The Metabolism of Naringin, Naringenin, and Apigenin
Description
This presentation explores the biochemical journey of three dietary flavonoids—naringin, naringenin, and apigenin—from oral ingestion through intestinal hydrolysis and absorption, hepatic Phase I and II metabolism, systemic circulation, and eventual excretion. Emphasis is placed on the role of intestinal and hepatic enzymes, transporters, and microbial metabolism in determining their bioavailability and biological activity.
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