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Gate and Fence function of the tight junction
Description
A Visualisation of the paracellular gate function and the transmembrane fence function of tight junctions. TJ proteins regulate the paracellular permeability of ions and molecules (gate function). Moreover, the TJ proteins limit the free diffusion of integral membrane proteins like channels or receptors. Thereby, the cell is polarized with an apical and a basolateral side.
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