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BioRender Template
Generic Organization of Class 1 and Class 2 CRISPR-Cas Loci
Description
This template shows the generic gene organization of Class 1 and Class 2 CRISPR-Cas loci as rows of labeled arrows representing genes. Class 1 loci contain cas3 plus large and small subunit genes (cas8 or cas10, cas11) along with cas7, cas5, cas6, cas1, cas2, and cas4, while Class 2 loci use tracrRNA with a single effector protein (cas9, cas12, or cas13) followed by cas1, cas2, and cas4, both ending in a CRISPR array of repeats and spacers.
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