Glucose restriction
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This template shows how protein, amino acid, and glucose restriction acts through insulin/IGF-1-like signaling to modulate AMPK, mTOR, PI3K/AKT, and glycolysis pathways, alongside their connections to the Krebs cycle and epigenetic regulators such as SIRTs, HATs, TETs, and JmjC. Text boxes below summarize downstream effects including transcriptional stress resistance, chromatin remodeling, and protection against aging-related diseases, while liver and muscle icons show amino acid, fatty acid, and ketone body exchange.
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This template shows how protein, amino acid, and glucose restriction acts through insulin/IGF-1-like signaling to modulate AMPK, mTOR, PI3K/AKT, and glycolysis pathways, alongside their connections to the Krebs cycle and epigenetic regulators such as SIRTs, HATs, TETs, and JmjC. Text boxes below summarize downstream effects including transcriptional stress resistance, chromatin remodeling, and protection against aging-related diseases, while liver and muscle icons show amino acid, fatty acid, and ketone body exchange.