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Glutamate Regulation
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Description:
Synaptic transmission emphasizing glutamate regulation. The diagram depicts glutamate accumulating in the synaptic cleft between pre- and post-synaptic neurons, highlighting its interaction with NMDA and AMPA receptors. Astrocytic involvement via EEAT2 is shown as a key mechanism in clearing excess glutamate to prevent excitotoxicity, with the therapeutic effects of riluzole mitigating overactivation of sodium channels and receptors.
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August 2026
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Synaptic transmission emphasizing glutamate regulation. The diagram depicts glutamate accumulating in the synaptic cleft between pre- and post-synaptic neurons, highlighting its interaction with NMDA and AMPA receptors. Astrocytic involvement via EEAT2 is shown as a key mechanism in clearing excess glutamate to prevent excitotoxicity, with the therapeutic effects of riluzole mitigating overactivation of sodium channels and receptors.








