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BioRender Template
GO-or-GROW Dichotomy in Malignant Glioma
Description
This template contrasts the proliferative "GROW" and invasive "GO" states of glioma cells, showing that GROW is favored under normoxia, abundant glucose, high miR-451, and high pOlig2, while GO is favored under hypoxia, glucose deprivation, high TNC expression, and high Wnt5a. Arrows indicate that metabolic stress and therapeutic intervention can push cells from a proliferative to an invasive state, with an unresolved question mark for the reverse transition.
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