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Gut-associated IgA+ immune cells regulate obesity-related insulin resistance
Creator
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Description
Graphical abstract of research article:
- B cell derived IgA is a crucial antibody that ensures mutualism with gut commensals.
- High fat diet feeding in mice compromises IgA production.
- IgA deficiency results in gut microbial dysbiosis, worsened intestinal permeability, inflammation and metabolic disease.
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