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Haematopoiesis in healthy adults
Creator
s
Description
HSC gives rise to itself and a lymphoid-myeloid progeny following generate of CMP or CLL. CMP produce: red blood cell (RBC); platelets; monocytes (macrophages) dendritic cells, neutrophils, eosinophils, basophils and mast cells; Lymphopoiesis gives rise: natural killer (NK) cells; B/T-lineage cells. The transcriptional factors: Bmi-1; GATA-2; Ikaros and Ikaros. T-cells maturation (naïve T-cells) in the thymus, following circulation until triggered cells differentiation (effector T-cells).
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