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BioRender Template
Histamine Inhibition of ERK
Description
This template shows histamine binding the H2 receptor to activate Gas protein, adenylyl cyclase, cAMP, and PKA, which inhibits c-Raf in the parallel TLR agonist pathway. The TLR pathway itself proceeds through Ras, c-Raf, MEK1/2, and ERK1/2 to activate AP-1 and produce TNF.
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