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BioRender Template
Host–bacterial interactions
Creator
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Description
Top left: Some commensal bacteria produce beneficial anti-inflammatory metabolites that are used by host cells to mediate homeostasis. Bottom left: macrophage-specific metabolic adaptations that promote pathogen death. Top right: S. typhimurium-mediated interference with macrophage metabolism, promoting infection. Bottom right: itaconate inhibits the glyoxalate cycle in bacteria, but P. aeruginosa and Y. pestis have adapted to metabolize itaconate and use it as a carbon source.
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