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How Dendritic Cells Become Competent to Stimulate T Cells

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Akiko Iwasaki

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BioRender Team

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Description: This template shows four steps in how dendritic cells become competent to stimulate T cells, starting with an immature dendritic cell recognizing PAMPs through receptors like DEC-205, DC-SIGN, and Dectin-1. TLR signaling induces CCR7 expression and antigen processing, allowing the dendritic cell to migrate to the lymph node and present antigenic peptide on MHC II to a naive T cell via the MHC II-TCR complex with CD80/CD86 and CD28 co-stimulation.

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What does the How Dendritic Cells Become Competent to Stimulate T Cells template show?

This template shows four steps in how dendritic cells become competent to stimulate T cells, starting with an immature dendritic cell recognizing PAMPs through receptors like DEC-205, DC-SIGN, and Dectin-1. TLR signaling induces CCR7 expression and antigen processing, allowing the dendritic cell to migrate to the lymph node and present antigenic peptide on MHC II to a naive T cell via the MHC II-TCR complex with CD80/CD86 and CD28 co-stimulation.

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