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BioRender Template
Hypoxia inducible factor inhibition to overcome sorafenib resistance in hepatocellular carcinoma
Creator
s
Description
In hepatocellular carcinoma cells treated with sorafenib, drug resistance is observed. Hypoxia-inducible factors that contribute to this sorafenib resistance are inhibited by any kind of HIF inhibitor. The effects of sorafenib in HCC cells are regained through this inhibition, which are apoptosis, proliferation, and angiogenesis.
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