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IgM and IgG Activate the Complement System
Description
This template shows how pentameric IgM adopts a staple conformation while surface-bound IgG molecules each bind bacterial antigens, and how both recruit C1q, which activates C1r and the serine protease C1s to trigger the complement cascade. Separate panels compare the IgM and IgG pathways side by side on a bacterial surface.
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