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Immune Function of the Spleen
Description
This template compares three pathways of immune tolerance induction in the spleen arising from tumor-derived apoptotic cells, trauma-derived apoptotic cells, and eye-derived apoptotic cells from anterior chamber-associated immune deviation. Each pathway shows marginal zone macrophages and dendritic cells signaling through molecules like ROS, IL-10, TGF-beta, and PD-L1 to expand regulatory T cells or suppress CD8 T cells in the white pulp, ultimately leading to tolerance induction.
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