Immunological synapse
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Description:
This template shows the molecular architecture of the immunological synapse between a T cell and a B cell, mapping receptor-ligand pairs such as TCR-MHC II, LFA1-ICAM1, CD28-CD80/86, PD-1-PD-L1/2, and CD2-CD48/CD59 along with downstream signaling components Lck, ZAP70, and CD3 zeta. A side panel shows a cross-sectional view of the synapse organized into concentric cSMAC, pSMAC, and dSMAC zones.
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This template shows the molecular architecture of the immunological synapse between a T cell and a B cell, mapping receptor-ligand pairs such as TCR-MHC II, LFA1-ICAM1, CD28-CD80/86, PD-1-PD-L1/2, and CD2-CD48/CD59 along with downstream signaling components Lck, ZAP70, and CD3 zeta. A side panel shows a cross-sectional view of the synapse organized into concentric cSMAC, pSMAC, and dSMAC zones.