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BioRender Template
Immunomodulation Functions of Macrolides
Description
This template shows how macrolide drugs modulate intracellular signaling from RTK, TLR, and GPCR receptors, blocking steps in the PLCgamma/IP3/calcium, MEK/ERK1/2, and TLR/NFkB pathways. The inhibited steps prevent activation of AP1 and NFkB transcription factors, blocking pro-inflammatory gene expression in the nucleus.
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