Immunotherapy ZA AKU
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Description:
This template shows engineered exosomes carrying anti-CSF1R siRNA, CRISPR/Cas9, or temozolomide used to shift macrophages from a pro-tumoral M1 phenotype, marked by CD80 and CSF1R signaling that stimulates immune response, toward an anti-tumoral phenotype marked by CD206 that reduces tumor cell proliferation, invasion, and matrix remodeling. It also shows CD34+ cells surrounded by exosome-targeted macrophages of both phenotypes.
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This template shows engineered exosomes carrying anti-CSF1R siRNA, CRISPR/Cas9, or temozolomide used to shift macrophages from a pro-tumoral M1 phenotype, marked by CD80 and CSF1R signaling that stimulates immune response, toward an anti-tumoral phenotype marked by CD206 that reduces tumor cell proliferation, invasion, and matrix remodeling. It also shows CD34+ cells surrounded by exosome-targeted macrophages of both phenotypes.