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Induction of 2nd Order Cytokines
Description
This template shows how dendritic cells and naive T cells drive induction of second order cytokines, tracing first order cytokines such as IL-6, IL-4, and IL-12 through transcription factors like Bcl6, GATA3, and T-bet to specific lymphocyte subsets. Each subset, including Tfh, TH2, TH1, TH17, and iTreg, is linked to its resulting second order cytokines such as IL-21, IL-4/5/13, IFN-gamma, IL-17, and IL-10/TGF-beta.
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