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Influence on autoimmune activity mediated by the gut microbiome in Rheumatoid Arthritis

Created by 
Tomas Wear
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Description:

The gut microbiome plays a crucial role in the development and progression of rheumatoid arthritis. Contributing factors such as epigenetic changes and altered microbiome diversity can lead to increased exposure to harmful bacteria. This exposure can compromise the gut barrier, allowing harmful substances to enter the bloodstream. This triggers an immune response, characterised by increased production of inflammatory molecules and autoantibodies. These immune complexes then circulate the body
Updated 
August 2026

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The gut microbiome plays a crucial role in the development and progression of rheumatoid arthritis. Contributing factors such as epigenetic changes and altered microbiome diversity can lead to increased exposure to harmful bacteria. This exposure can compromise the gut barrier, allowing harmful substances to enter the bloodstream. This triggers an immune response, characterised by increased production of inflammatory molecules and autoantibodies. These immune complexes then circulate the body

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