BioRender Template

Innate Immune Antagonism by SARS-CoV

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Jessica Tucker

•

BioRender Team

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Description: This template shows how SARS-CoV proteins antagonize the innate immune response, with viral proteins such as N, M, PLPro, nsp1, ORF3b, and ORF6 blocking RIG-I and MDA5 sensing, MAVS and Traf6 signaling, IRF3, IRF7, and NF-kB activation, and JAK-STAT signaling downstream of the type I interferon receptor. The pathway is split into two cell compartments showing suppression of both interferon-beta production and interferon-stimulated gene expression.

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What does the Innate Immune Antagonism by SARS-CoV template show?

This template shows how SARS-CoV proteins antagonize the innate immune response, with viral proteins such as N, M, PLPro, nsp1, ORF3b, and ORF6 blocking RIG-I and MDA5 sensing, MAVS and Traf6 signaling, IRF3, IRF7, and NF-kB activation, and JAK-STAT signaling downstream of the type I interferon receptor. The pathway is split into two cell compartments showing suppression of both interferon-beta production and interferon-stimulated gene expression.

Is the Innate Immune Antagonism by SARS-CoV template free to use?

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