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Intracellular life cycle of B. pseudomallei: Mechanisms of host cell invasion, survival and spread

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Annika Hinze

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Description: • Adhesion to and invasion of host cell o Pili, fimbriae, adhesion proteins BoaA, BoaB • Phagosomal survival o OxyR, KatG, AhpC; speG, dpsA • Phagosomal escape o T3SS • Intracellular adaption and replication o BLF1 • Cell-to-cell spread o Host actin polymerisation o BimA o Fusion of host cell membranes to MNGCs o T6SS

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What does the Intracellular life cycle of B. pseudomallei: Mechanisms of host cell invasion, survival and spread template show?

• Adhesion to and invasion of host cell o Pili, fimbriae, adhesion proteins BoaA, BoaB • Phagosomal survival o OxyR, KatG, AhpC; speG, dpsA • Phagosomal escape o T3SS • Intracellular adaption and replication o BLF1 • Cell-to-cell spread o Host actin polymerisation o BimA o Fusion of host cell membranes to MNGCs o T6SS

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