Ipilimumab project
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Description:
This template shows how ipilimumab restores T cell activation by binding CTLA-4, preventing it from outcompeting CD28 for B7 binding on the antigen-presenting cell. It compares an active T cell, an inactive T cell blocked by CTLA-4, and an active T cell in the presence of ipilimumab, with a key labeling TCR, MHC, B7, CD28, and CTLA-4.
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This template shows how ipilimumab restores T cell activation by binding CTLA-4, preventing it from outcompeting CD28 for B7 binding on the antigen-presenting cell. It compares an active T cell, an inactive T cell blocked by CTLA-4, and an active T cell in the presence of ipilimumab, with a key labeling TCR, MHC, B7, CD28, and CTLA-4.