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BioRender Template
JAK Inhibitors for Crohn's Disease
Description
This template shows six cytokine receptor pairs at the immune cell membrane, each labeled with its JAK/TYK subunit combination (such as TYK2-JAK2, JAK1-JAK2, JAK1-JAK3) and the cytokines they respond to, including IL-12, IL-23, type I interferon, and IL-2/4/7. Brackets above indicate which JAK inhibitor drugs, such as tofacitinib, upadacitinib, and ritlecitinib, target which receptor combinations for treating Crohn's disease.
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