BioRender Template

Keap1–Nrf2 Pathway

Created by 
Samara Ona
  •  
BioRender Team
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Description:

The Keap1-Nrf2 pathway is a signaling pathway involved in cellular responses to oxidative stress. The regulatory protein Keap1 regulates the activity of the transcription factor Nrf2. Under conditions of oxidative stress, Nrf2 is released from Keap1 and translocates to the nucleus, where it activates the expression of genes encoding antioxidant enzymes This pathway plays an important role in cell defense against oxidative damage and redox maintenance of homeostasis. [Template description adapted from GPT3.5, 2023]
Updated 
August 2026

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What does the Keap1–Nrf2 Pathway template show?

The Keap1-Nrf2 pathway is a signaling pathway involved in cellular responses to oxidative stress. The regulatory protein Keap1 regulates the activity of the transcription factor Nrf2. Under conditions of oxidative stress, Nrf2 is released from Keap1 and translocates to the nucleus, where it activates the expression of genes encoding antioxidant enzymes This pathway plays an important role in cell defense against oxidative damage and redox maintenance of homeostasis. [Template description adapted from GPT3.5, 2023]

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