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Ketamine and Cognition Impairment
Description
This template shows how repeated pre-adolescent exposure to sub-anesthetic ketamine doses affects the rat hippocampus, tested through social interaction, novel object recognition, elevated plus maze, and fear conditioning assays. Results show decreased social interaction and recognition memory, no significant change in anxiety-like behavior, and reduced NMDAR-dependent long-term potentiation with increased neuronal cell death.
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