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Killing of Infected Epithelia by Intraepithelial Lymphocytes (IEL)
Description
This template shows a three-panel sequence of virus infecting a mucosal epithelial cell, the infected cell displaying viral peptide via MHC class I to a CD8 intraepithelial lymphocyte (IEL), and the activated IEL killing the infected cell through perforin, granzyme, and Fas-Fas ligand pathways. The panels are set within the gut lumen and lamina propria tissue layers.
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